Introduction
Human nerve cells are incapable of regrowing on their own. People suffer from spinal cord injuries, stroke, diseases, and other conditions that involve death or damage to the neurons that don't recover. A patient's fat can help repair injury to the spinal cord. After the primary injury, microenvironmental changes inhibit axonal regeneration. Stem cells can provide trophic support to the injured spinal cord microenvironment.. According to Ohta and colleagues, tests in animal models confirmed that the injected cells survived without immunosuppression drugs and that the DFAT-grafted animals showed significantly better motor function than controls. Because there is a fixed number of human nerve cells at birth, it is difficult for the cells to repair itself after injuries.
Process
Human nerve cells are incapable of regrowing after an injury occurs. People who suffer from spinal cord injuries, stroke, diseases, and
other conditions that could cause death or damage to the neurons have dificultades recovering. A patient's fat can help repair injury to the
spinal cord. After the primary injury, microenvironmental changes inhibit axonal regeneration. Stem cells can provide trophic support to
the injured spinal cord microenvironment by modulating the response. There have been testes using the fat tissues in the animal
model to come up with something that behaves similar to nerve cell's. The DFAT-grafted animals showed significantly better motor
function than controls but it is unclear weather theses cells can be useful neurodegeneritive diseases
Evaluation
Same as process
Conclusion
If stem cells can be obtained by a patient’s own fat, it can be used to help repair injury to the spinal cord. By a new source of cell replacement therapy, central nervous system disorders in humans can be treated. Studies have suggested that transplanted fat cells can restore function after spinal cord injury. Stem cells have trófica support to the spinal cord. After an injury the injury can lead to a microenvironmental changes that inhibit axonal regeneration. Because there is a fixed number of human nerve cells at birth, it is difficult for the cells to repair itself after injuries.